Konstantoglou has worked as a principal research associate at the Energy Technologies Division, of Lawrence Berkeley National Laboratory (LBNL). Member of the Windows & Daylighting Group she conducted research on dynamic facades by qualifying and quantifying the performance of advanced daylighting and complex fenestration systems. Because of her background studies on architecture and environmental design she got involved in the development of simulation tools such as Comfen.

As a research associate at LBNL, Konstantoglou has worked in the eLAD project, a grant-supported project by the US Department of Energy (DOE) that aimed to develop an e-Learning platform for lighting and daylighting. Working with large interdisciplinary teams including architects, engineers and software designers, Konstantoglou got involved in all phases of the project from curriculum definition to interface development and 3D visualizations.

Maria Konstantoglou has worked as an architect at Skidmore, Owings & Merrill (SOM) in the San Francisco office and got involved in projects of various scale and type throughout the United States and China. Believing in the significance of sustainability in the built environment her main work goal was to bring research methods and computer modeling to architectural design solutions. Prior to her move to the US Konstantoglou worked in the architecture office of Astrinidou Associates in Thessaloniki, Greece focusing on the conservation project of the municipality of Sykies that aimed to restore and reuse houses built by refugees onto and close to the Byzantine Walls of the city.

Her research conducted during her MPhil and PhD studies has been awarded by the Ph.D Scholarship Programme “Heraclitus II”, co-funded by the European Union and the EPSRC grant in the UK. She has also been awarded by the Fulbright and IKY scholarship.